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BeOne Medicines Announces IMDELLTRA Royalty Purchase Agreement for up to $950 Million

BeOne Medicines Ltd. (ONC) | August 25, 2025

By Alice Johnson

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BeOne Medicines has entered into an agreement to sell its royalty rights on the worldwide sales, excluding China, of Amgen's IMDELLTRA for up to $950 million to Royalty Pharma.

IMDELLTRA is a first-in-class immunotherapy indicated for the treatment of adult patients with extensive-stage small cell lung cancer.

The agreement includes an upfront payment of $885 million with the option to sell remaining royalties within 12 months for up to $65 million.

Royalty Purchase Agreement

Royalty Pharma to acquire BeOne's royalties on IMDELLTRA for up to $950 million, providing BeOne with substantial upfront payment and future selling opportunities.

IMDELLTRA Description

IMDELLTRA is a DLL-3 targeting bispecific T-cell engager approved for patients with extensive-stage small cell lung cancer after platinum-based chemotherapy.

Collaboration Benefits

The agreement accelerates value realization for BeOne while maintaining participation in the long-term potential of IMDELLTRA.

  • The agreement with Royalty Pharma provides BeOne with financial flexibility and operational agility.
  • BeOne's collaboration with Amgen has been instrumental in advancing its mission to deliver transformative oncology medicines globally.

The IMDELLTRA Royalty Purchase Agreement marks a significant milestone for BeOne Medicines, demonstrating the value of their collaboration with Amgen. This strategic move positions BeOne for continued success and innovation in the oncology sector.