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C4 Therapeutics Outlines Strategic Milestones for Advancing Cemsidomide

C4 Therapeutics (CCCC) | Jan. 14, 2026

By Laura Young

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C4 Therapeutics, a clinical-stage biopharmaceutical company, detailed strategic milestones through 2028.

They highlighted the advancement of cemsidomide as a potential best-in-class IKZF1/3 degrader and a focused discovery strategy on novel targets.

Trials for cemsidomide are on track, with the Phase 2 MOMENTUM trial set to begin in Q1 2026.

Cemsidomide Trials Progress

Initiate Phase 2 MOMENTUM trial in Q1 2026 and Phase 1b trial in Q2 2026, exploring combinations with other therapies.

Internal Discovery Strategy

Focused on inflammation, neuro-inflammation, and neuro-degenerative diseases with novel targets in validated pathways.

Financial Position

Cash runway extends to the end of 2028, providing funding through key milestones.

  • C4T aims to become a fully integrated biopharmaceutical company leveraging targeted protein degradation for breakthrough therapies.
  • The company's strong balance sheet ensures continued progress in advancing their portfolio and creating transformative medicines.

C4 Therapeutics demonstrates a strong commitment to advancing cemsidomide and pioneering therapies for challenging diseases.