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Traws Pharma Reports Positive Interim Clinical Data with Ratutrelvir Versus PAXLOVID™

Traws Pharma, Inc. (TRAW) | December 17, 2025

By Zane Campbell

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Traws Pharma announced positive interim data with ratutrelvir, a novel therapy for COVID-19.

Ratutrelvir demonstrated a differentiated clinical profile compared to PAXLOVID™, showing fewer adverse events and no viral rebounds.

The study included patients ineligible for ritonavir-boosted regimens, addressing a significant population with limited treatment options.

Differentiated Clinical Profile

Ratutrelvir showed fewer adverse events and no viral rebounds compared to PAXLOVID™.

Inclusivity in Treatment

Patients ineligible for ritonavir-boosted regimens were included in the study.

Favorable Tolerability Profile

Ratutrelvir exhibited a favorable tolerability profile with fewer adverse events.

Efficacy Signal

Ratutrelvir-treated patients showed time-to-sustained symptom alleviation comparable to PAXLOVID™.

Long-COVID Potential

Ratutrelvir may have utility in reducing post-acute sequelae of SARS-CoV-2 infection.

  • Ratutrelvir demonstrated efficacy and favorable tolerability in the interim analysis.
  • The study results support the continued evaluation of ratutrelvir in COVID-19 patients.
  • Potential implications for treating Long-COVID suggest a broader application for ratutrelvir.

The interim data highlights the promising potential of ratutrelvir in treating COVID-19, with a differentiated clinical profile and favorable tolerability. Further evaluation is warranted to explore its utility in addressing critical threats to human health.