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Werewolf Therapeutics Presents Clinically Validated Technology for Cancer Immunotherapies

Werewolf Therapeutics (WERE) | December 2025

By Zane Campbell

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Werewolf Therapeutics, a biotech company, presented its clinically validated technology addressing limitations in potent cancer immunotherapies.

The company's PREDATOR® platform focuses on creating novel, conditionally activated biologics through differentiated masking and linker technology.

Key product candidates include INDUKINE (inducible cytokine) and INDUCER (inducible T cell engager) molecules with promising efficacy and tolerability profiles.

WTX-124 (IL-2)

Potential best-in-class efficacy and tolerability profile observed in Phase 1/1b trial, showing 30% ORR in a subset of melanoma patients.

WTX-330 (IL-12)

Demonstrated anti-tumor activity and improved therapeutic index in FIH study, with enhanced tolerability and efficacy.

  • The presentation highlighted Werewolf Therapeutics' progress in developing innovative cancer immunotherapies with the potential to address current limitations in the field.
  • Key milestones include upcoming data release for WTX-124 and ongoing efforts to secure strategic partnerships for further development.

Werewolf Therapeutics' focus on novel biologics and promising clinical results positions it as a key player in advancing cancer immunotherapy treatments.