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Traws Pharma Receives Approval for Phase 2 COVID Studies with Ratutrelvir

Traws Pharma (TRAW) | August 18, 2025

By Sam Nelson

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Traws Pharma has received approval to proceed with Phase 2 studies for ratutrelvir, a ritonavir-free treatment for COVID-19.

The trials will assess safety, efficacy, disease rebound, and incidence of Long COVID compared to PAXLOVID®.

Top-line data from the trials is expected by year-end 2025.

Phase 2 Trials Initiated

Traws Pharma has initiated Phase 2 trials for ratutrelvir in COVID subjects, aiming for significant results by year-end 2025.

Comparison with PAXLOVID®

The study will compare ratutrelvir with PAXLOVID®, assessing safety and efficacy in COVID patients.

Potential Best-in-Class Agent

Ratutrelvir, a ritonavir-free agent, shows potential to become a new standard of care for COVID treatment.

  • Traws Pharma's ratutrelvir has the potential to address shortcomings of current COVID treatments.
  • The ritonavir-free profile of ratutrelvir allows for once-daily dosing, reducing the risk of disease rebound and Long COVID.

These Phase 2 trials mark a crucial step in evaluating the effectiveness of ratutrelvir against COVID-19, offering hope for improved treatments. Results expected by year-end 2025 will determine its future as a potential game-changer in COVID therapeutics.