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Q32 Bio Sells Complement Inhibitor ADX-097 to Akebia Therapeutics

Q32 Bio Inc. (QTTB) | December 1, 2025

By Charlie Brown

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Q32 Bio has sold its Phase 2 complement inhibitor, ADX-097, to Akebia Therapeutics, Inc.

The asset sale will provide Q32 Bio with additional cash and extend its financial runway into the second half of 2027

Q32 Bio remains focused on advancing bempikibart for alopecia areata, aiming to address significant unmet medical needs

Financial Boost

$12 million in upfront and guaranteed near-term milestone payments will support Q32 Bio's operations and development plans

Potential Revenue

Q32 Bio could receive up to $592 million, including upfront payments, milestone achievements, and future royalties from the sale of ADX-097

Strategic Focus

Q32 Bio retains its tissue-targeted complement inhibitor platform and evaluates options for other early-stage assets

  • The sale of ADX-097 strengthens Q32 Bio's financial position and enables a continued focus on bempikibart development
  • This transaction aligns with Q32 Bio's strategy to advance innovative therapies for alopecia areata and autoimmune diseases

Q32 Bio's sale of ADX-097 marks a strategic move to bolster financial resources while maintaining dedication to advancing treatments for alopecia areata and related diseases.