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ProtoKinetix Mourns Loss of President and CEO, Announces Successor

ProtoKinetix Incorporated (PKTX) | November 17, 2025

By Fiona Wilson

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ProtoKinetix, Incorporated announces the tragic loss of President and CEO Clarence E. Smith in an accident.

Michael Guzzetta appointed as the successor to Clarence E. Smith.

The company deeply expresses condolences for the loss and acknowledges Clarence Smith's significant contributions.

Loss of Clarence E. Smith

President and CEO of ProtoKinetix, appointed in 2015, passed away in a tragic accident on November 13, 2025.

Appointment of Michael Guzzetta

Chief Financial Officer appointed as Chairman of the Board, President, and CEO following Clarence E. Smith's demise.

  • The sudden loss of Clarence E. Smith will have a significant impact on the leadership and future direction of ProtoKinetix.
  • Michael Guzzetta stepping into multiple leadership roles marks a transitional phase for the company.

ProtoKinetix faces a challenging period as they navigate the aftermath of the loss of Clarence E. Smith and the transition to new leadership under Michael Guzzetta.