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MBX Biosciences Provides 2026 Outlook and Business Update at J.P. Morgan Healthcare Conference

MBX Biosciences (MBX) | January 11, 2026

By Quinn Adams

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MBX Biosciences announces key milestones for 2026 including Phase 2 trial data and new obesity candidates nominations.

The company's precision peptide therapies show promise for treating endocrine and metabolic disorders.

Strong cash position with approximately $373.7 million as of December 31, 2025, supporting operations into 2029.

Successful Phase 2 Trial

Avail trial of once-weekly canvuparatide for hypoparathyroidism achieved primary endpoint with high responder rates.

Expanding Obesity Pipeline

Progress on MBX 4291 and plans for new obesity candidates nominations in 2026.

Long-acting Imapextide Progress

Updates on Phase 2a trial results and patient preferences for once-weekly injections.

Financial Strength

Preliminary unaudited cash reserves of $373.7 million to support operations into 2029.

  • Successful Phase 2 trial sets stage for pivotal Phase 3 trial for hypoparathyroidism treatment.
  • Expansion of obesity pipeline with potential once-monthly dosing candidates expected to address patient needs.
  • Positive feedback on long-acting Imapextide's trial results and patient preferences highlight market potential.
  • Strong financial position provides stability for long-term pipeline growth and strategic investments.

MBX Biosciences' robust pipeline progress and financial stability position the company for a catalyst-rich 2026.