(DumbMoney)

Explore the latest updates and key analyses on companies, markets, and industry trends.


Lipocine's PPD Phase 3 Study (LPCN 1154) Hits 80% Enrollment Milestone

Lipocine Inc. (LPCN) | December 15, 2025

By Tina Carter

image

Lipocine Inc. announced 80% completion of enrollment in the Phase 3 clinical trial for LPCN 1154.

The trial evaluates LPCN 1154 for the rapid relief treatment of Postpartum Depression (PPD).

Second Drug Safety Monitoring Board meeting update is planned for mid-January 2026.

Enrollment Milestone Reached

80% enrollment milestone achieved in the Phase 3 trial evaluating LPCN 1154 for PPD.

DSMB Meeting Update

Second Drug Safety Monitoring Board meeting update scheduled for mid-January 2026.

Topline Results

Topline results for LPCN 1154 on track to be announced in the second quarter of 2026.

  • The encouraging recruiting rate reflects potential unmet medical needs in the treatment of PPD.
  • DSMB recommended continuation of the trial without modification after the first review.
  • Data from the Phase 3 trial set to support a 505(b)(2) NDA submission for LPCN 1154 in 2026.

Lipocine's progress in the Phase 3 trial indicates promising outcomes in addressing the challenges of PPD treatment. The upcoming DSMB meeting and the anticipated topline results are crucial milestones for the company's development pipeline.