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Harmony Biosciences Guides to Over $1 Billion in WAKIX® Revenue in 2026

Harmony Biosciences Holdings, Inc. (HRMY) | Jan. 12, 2026

By Uma Mitchell

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Harmony Biosciences projects robust revenue growth for 2026, with preliminary net revenue of $868 million in 2025.

The company is on track to achieve blockbuster status in narcolepsy with WAKIX.

Harmony Biosciences is advancing its late-stage pipeline with promising formulations and ongoing clinical trials.

WAKIX Revenue Projection

2026 guidance suggests WAKIX net revenue of $1.0 - $1.04 billion, indicating strong growth potential.

Pitolisant Franchise Expansion

Strategic initiatives aim to extend the pitolisant franchise, introducing next-gen formulations for long-term value creation.

Robust Pipeline Development

The company's pipeline includes five ongoing Phase 3 registrational trials, targeting distinct CNS indications for future growth.

  • Harmony Biosciences reported strong preliminary net product revenue for Q4 2025, showcasing consistent growth.
  • The company's innovative strategies in narcolepsy treatment and pipeline advancements position it for sustained success in the biotech industry.

With a solid financial performance in 2025 and optimistic revenue guidance for 2026, Harmony Biosciences demonstrates resilience and innovation in the pharmaceutical sector, signaling potential for long-term growth and value creation.