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CG Oncology Provides Updated Timeline for PIVOT-006 Phase 3 Topline Data in Intermediate-Risk NMIBC

CG Oncology (CGON) | January 9, 2026

By Alice Johnson

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CG Oncology announced an expedited timeline for the topline data readout for the Phase 3 PIVOT-006 clinical trial.

The topline data is now expected in the first half of 2026 for evaluating cretostimogene monotherapy in intermediate-risk NMIBC.

PIVOT-006 is the first Phase 3 randomized trial in this patient population with over 90 sites participating.

Topline Data Expectation

Phase 3 topline data for PIVOT-006 expected in the first half of 2026, nearly one year ahead of schedule.

Investigational Therapy

PIVOT-006 is the first randomized registrational trial to evaluate an investigational therapy in intermediate-risk NMIBC.

Population Impact

The IR patient population is estimated to be greater than fifty thousand patients in the United States.

  • The expedited timeline of topline data indicates significant progress in the Phase 3 clinical trial for intermediate-risk NMIBC.
  • Broad participation across academic and community sites highlights the trial's real-world relevance and potential impact on patients with IR NMIBC.

CG Oncology's accelerated timeline for PIVOT-006 Phase 3 data shows promising developments in the evaluation of cretostimogene monotherapy for intermediate-risk NMIBC patients.