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Athira Pharma Announces Exclusive License to Lasofoxifene Phase 3 Development Program for Metastatic Breast Cancer Candidate and a Financing for up to $236 Million

Athira Pharma (ATHA) | December 18, 2025

By Wendy Roberts

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Athira Pharma has acquired exclusive rights to develop and commercialize lasofoxifene for metastatic breast cancer.

The Phase 3 clinical trial for lasofoxifene is currently over 50% enrolled, with data expected in mid-2027.

The company secured a significant financing of up to $236 million to support the development of the Phase 3 program.

Exclusive License Acquisition

Acquired exclusive global license (excluding Asia and certain countries in the Middle East) from Sermonix Pharmaceuticals for lasofoxifene development.

Phase 3 Trial Progress

Phase 3 ELAINE-3 trial is over 50% enrolled, on track for data readout in mid-2027.

Financial Support

Secured $90 million upfront financing with potential additional $146 million through warrants for key milestones.

  • Lasofoxifene shows promise in treating ESR1-mutant metastatic breast cancer patients.
  • Potential to provide meaningful combination efficacy with tolerability benefits.
  • Expected to establish lasofoxifene as a preferred endocrine therapy for certain breast cancer patients.

Athira Pharma's acquisition of lasofoxifene's development rights and significant financing mark a pivotal moment for the company, poised to revolutionize the treatment of metastatic breast cancer.