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Aldeyra Receives Fast Track Designation for ADX-2191 in Retinitis Pigmentosa Treatment

Aldeyra Therapeutics (ALDX) | August 19, 2025

By Yara Phillips

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Aldeyra Therapeutics received Fast Track Designation from the FDA for ADX-2191 to treat retinitis pigmentosa, a rare genetic eye disease.

There is currently no approved treatment for most forms of retinitis pigmentosa affecting over one million people worldwide.

Fast Track Designation highlights the potential of ADX-2191 to address the unmet medical need in ophthalmology.

Fast Track Designation Granted

The FDA granted Fast Track Designation for ADX-2191, emphasizing its potential to treat retinitis pigmentosa effectively.

Encouraging Phase 2 Results

Results from a Phase 2 clinical trial in 2023 showed improvements in retinal sensitivity after ADX-2191 treatment.

Upcoming Phase 2/3 Trial

A Phase 2/3 clinical trial for ADX-2191 in retinitis pigmentosa is set to commence in 2025.

  • Fast Track Designation accelerates drug development and review for serious conditions like retinitis pigmentosa.
  • ADX-2191's potential to improve retinal sensitivity offers hope for patients with this progressive eye disease.

Aldeyra's Fast Track Designation for ADX-2191 underscores the urgency in finding effective treatments for retinitis pigmentosa, bringing hope to patients worldwide.