(DumbMoney)

Explore the latest updates and key analyses on companies, markets, and industry trends.


Acrivon Therapeutics Announces Positive Phase 2b Endometrial Cancer Clinical Data and New Development Candidate

Acrivon Therapeutics (ACRV) | January 8, 2026

By Paula Scott

image

Acrivon Therapeutics announced positive Phase 2b clinical data for ACR-368 in endometrial cancer.

Initial data from ACR-2316 Phase 1 study showed favorable tolerability and tumor shrinkage in multiple tumor types.

ACR-6840, a potential CDK11 inhibitor, selected as the next development candidate.

Positive Phase 2b Data for ACR-368

ACR-368 showed a 39% overall response rate in endometrial cancer patients with ≥2 prior lines of therapy.

ACR-2316 Phase 1 Study Update

Favorable tolerability and tumor shrinkage observed in subjects receiving ACR-2316, a WEE1/PKMYT1 inhibitor.

ACR-6840 Development

ACR-6840, a CDK11 inhibitor, nominated as the next preclinical development candidate.

  • Promising response rates in endometrial cancer patients with ACR-368.
  • Encouraging results in multiple tumor types with ACR-2316.
  • Potential of ACR-6840 as a first-in-class CDK11 inhibitor.

Acrivon Therapeutics is making significant progress in its pipeline with positive clinical data and the nomination of a new development candidate. The company's focus on precision medicines for high-value opportunities shows promise for future growth and innovation.